We hope you don’t need it, but if you do, Laminil is available now in the US, Canada, Australia, and Dubai.

Who Invented Laminil?

Twenty-eight years ago, Charles Owen, a farrier by training known to most as Charlie, began his amazing journey to unlock the mystery of laminitis. Starting with an idea of how laminitis originated, Charlie spent the next 17 years conducting a methodical research program to refine and validate his theory of the laminitis cascade, the chain of biochemical events that leads to laminitis. A self-educated scientist, Charlie, turned to Colorado State University to test his basic theory that the laminitis cascade can be stopped at the mast cell.

With his basic theory confirmed, the task was to find a drug that would interrupt and halt the laminitis cascade by inhibiting mast cell. Charlie contacted a major hospital that specialized in immune system treatments, and they pointed to some compounds that might succeed. He tested the compounds in the CSU laboratory and found that cromone molecules—cromolyn and nedocromil—appeared promising. He filed patents on the use of these drugs to treat laminitis under the copyrighted name Laminil©.

Next, Charlie arranged proof of concept studies on horses that had been artificially induced with laminitis. He devised the limb perfusion to deliver the drug to the affected area and converged on the appropriate dose through successive trials. In clinical studies, horses treated with Laminil recovered significantly faster than horses treated with a placebo.

With proof of concept confirmed, Charlie took Laminil to the field to test it on horses with naturally occurring laminitis. Over a hundred horses were involved in the field study. The results showed that Laminil can stop laminitis.

Charlie’s theory of laminitis was confirmed. His concept of intercepting the laminitis cascade at the mast cell was validated. His discovery of cromone molecules as effective mast cell inhibiters was clearly established. Decades of devotion and persistence came to fruition in Laminil and the new hope for horses with laminitis.